Urine-Based Liquid Biopsy for Nonurological Cancers.

08:00 EDT 1st April 2019 | BioPortfolio

Summary of "Urine-Based Liquid Biopsy for Nonurological Cancers."

The use of circulating cell-free DNA for detection of cancer genetics has been studied extensively. Liquid biopsy often refers to the use of blood as a minimally invasive source of body fluid for detecting circulating tumor DNA (ctDNA). However, urine collection, which is completely noninvasive, has been shown to also have great promise to serve as an alternate body fluid source for ctDNA. In this review article, we focus on the clinical utility of urine for genetic liquid biopsy of nonurological cancers.


Journal Details

This article was published in the following journal.

Name: Genetic testing and molecular biomarkers
ISSN: 1945-0257
Pages: 277-283


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Medical and Biotech [MESH] Definitions

Conducting a biopsy procedure with the aid of a MEDICAL IMAGING modality.

The removal of a soluble component from a liquid mixture by contact with a second liquid, immiscible with the carrier liquid, in which the component is preferentially soluble. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Discharge of URINE, liquid waste processed by the KIDNEY, from the body.

Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.

Miniaturized methods of liquid-liquid extraction.

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