Advertisement

Topics

Intramolecular hydroamination of selenoalkynes to 2-selenylindole in absence of catalyst.

08:00 EDT 15th April 2019 | BioPortfolio

Summary of "Intramolecular hydroamination of selenoalkynes to 2-selenylindole in absence of catalyst."

In this work, a series of 2-chalcogenylindoles were synthesized by an efficient new methodology, starting from chalcogenoalkynes, including an inedited tellurium indole derivative. For the first time, these 2-substituted chalcogenylindoles were obtained in the absence of metal catalyst or base, under thermal conditions only. In addition, the results described herein represent a methodology with inverse regioselectivity for the chalcogen functionalisation of indoles.

Affiliation

Journal Details

This article was published in the following journal.

Name: Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Pages:

Links

DeepDyve research library

PubMed Articles [4116 Associated PubMed Articles listed on BioPortfolio]

Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles.

Herein we report a practical two-step synthetic route to α-arylpyrrolidines consisting of Suzuki-Miyaura cross-coupling and enantioselective copper-catalyzed intramolecular hydroamination reactions. ...

Efficient 1,3-oxazolidin-2-one synthesis through heterogeneous Pd(II)-catalyzed intramolecular hydroamination of propargylic carbamates.

Herein, we present an operationally simple protocol for the cycloisomerisation of propargylic carbamates that uses a heterogeneous catalyst consisting of Pd nanoparticles immobilized on amino-function...

Regio- and Enantioselective Formal Hydroamination of Enamines for the Synthesis of 1,2-Diamines.

The asymmetric formal hydroamination of enamines using Cu-H catalyst is reported. The method provides a straightforward and efficient approach for the synthesis of chiral 1,2-dialkyl amines in good yi...

Redox-responsive phosphonite gold complexes in hydroamination catalysis.

Very high activities were observed in the redox-induced hydroamination of alkynes by employing a redox-active gold(i) complex featuring an electron-deficient, terphenyl-substituted phosphonite-based l...

Regio- and Enantioselective Intramolecular Amide Carbene Insertion into Primary C‒H Bonds using Ru(II)-Pheox Catalyst.

We have established a method for the highly regio- and enantioselective functionalization of tert-butyl groups via intramolecular amide carbene insertion to C‒H bonds, yielding γ-lactams with 91% e...

Clinical Trials [838 Associated Clinical Trials listed on BioPortfolio]

Why Are Patients With Absence Seizures Absent? A Brain Imaging Study

Our study examines which different brain regions are involved in child absence seizures and how they are related to attention and cognition.

Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study

The purpose of this study is to determine the best initial treatment for childhood absence epilepsy.

Search for Genes Influencing Childhood Absence Epilepsy Study

The purpose of our study is to identify gene(s) involved in the cause of childhood absence epilepsy (CAE).

A Pilot Study of Efficacy and Tolerability of Levetiracetam Monotherapy in Subjects With Childhood Absence Epilepsy

Childhood absence epilepsy (CAE) is a form of generalized epilepsy syndrome. Clinically these seizures are manifest with a sudden, brief (3-15 second) loss of awareness followed by a quic...

A SU2C Catalyst® Trial of a PD1 Inhibitor With or Without a Vitamin D Analog for the Maintenance of Pancreatic Cancer

Chemotherapy regimens for pancreatic cancer can now stabilize a patient's cancer and/or place some patients in remission or partial remission. The challenge now is to find options for main...

Medical and Biotech [MESH] Definitions

The total absence of teeth from either the mandible or the maxilla, but not both. Total absence of teeth from both is MOUTH, EDENTULOUS. Partial absence of teeth in either is JAW, EDENTULOUS, PARTIALLY.

The leveraging of collective wisdom within an organization as a catalyst to increase responsiveness and innovation.

A condition characterized by the complete absence of SEMEN. This disorder should be differentiated from AZOOSPERMIA, absence of sperm in the semen.

Enzymes of the isomerase class that catalyze the transfer of acyl-, phospho-, amino- or other groups from one position within a molecule to another. EC 5.4.

The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article