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In this work, a series of 2-chalcogenylindoles were synthesized by an efficient new methodology, starting from chalcogenoalkynes, including an inedited tellurium indole derivative. For the first time, these 2-substituted chalcogenylindoles were obtained in the absence of metal catalyst or base, under thermal conditions only. In addition, the results described herein represent a methodology with inverse regioselectivity for the chalcogen functionalisation of indoles.
This article was published in the following journal.
Name: Chemistry (Weinheim an der Bergstrasse, Germany)
Herein we report a practical two-step synthetic route to α-arylpyrrolidines consisting of Suzuki-Miyaura cross-coupling and enantioselective copper-catalyzed intramolecular hydroamination reactions. ...
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Our study examines which different brain regions are involved in child absence seizures and how they are related to attention and cognition.
The purpose of this study is to determine the best initial treatment for childhood absence epilepsy.
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The total absence of teeth from either the mandible or the maxilla, but not both. Total absence of teeth from both is MOUTH, EDENTULOUS. Partial absence of teeth in either is JAW, EDENTULOUS, PARTIALLY.
The leveraging of collective wisdom within an organization as a catalyst to increase responsiveness and innovation.
A condition characterized by the complete absence of SEMEN. This disorder should be differentiated from AZOOSPERMIA, absence of sperm in the semen.
Enzymes of the isomerase class that catalyze the transfer of acyl-, phospho-, amino- or other groups from one position within a molecule to another. EC 5.4.
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.