Intramolecular hydroamination of selenoalkynes to 2-selenylindole in absence of catalyst.

08:00 EDT 15th April 2019 | BioPortfolio

Summary of "Intramolecular hydroamination of selenoalkynes to 2-selenylindole in absence of catalyst."

In this work, a series of 2-chalcogenylindoles were synthesized by an efficient new methodology, starting from chalcogenoalkynes, including an inedited tellurium indole derivative. For the first time, these 2-substituted chalcogenylindoles were obtained in the absence of metal catalyst or base, under thermal conditions only. In addition, the results described herein represent a methodology with inverse regioselectivity for the chalcogen functionalisation of indoles.


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Name: Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765


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