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Hydrochlorothiazide-Induced Photosensitivity in a Psoriasis Patient Following Exposure to Narrow-Band UVB Excimer Therapy.

08:00 EDT 21st April 2019 | BioPortfolio

Summary of "Hydrochlorothiazide-Induced Photosensitivity in a Psoriasis Patient Following Exposure to Narrow-Band UVB Excimer Therapy."

Drug-induced photosensitivity develops when use of oral or topical photosensitizing medications creates a rash after exposure to ultraviolet radiation. Medications most commonly implicated in photosensitive-drug reactions include amiodarone, nonsteroidal anti-inflammatories, thiazides, tetracycline antibiotics, chlorpromazine, and fluoroquinolones. It is generally believed that drug-induced photosensitivity is an ultraviolet A phenomenon, caused by ultraviolet wavelengths between 315 and 400 nanometers. Here, we present a case of hydrochlorothiazide-induced photosensitivity following exposure to 308nm narrow-band ultraviolet B light emitted from an excimer laser in a patient undergoing treatment for plaque psoriasis. This patient had received biweekly treatments with the excimer laser for years prior without any history of adverse reactions. We believe that our patient suffered an acute photosensitivity to ultraviolet B due to new-onset hydrochlorothiazide. Because narrow-band ultraviolet B-emitting lasers are used to treat many dermatologic conditions, physicians should be aware of potential photosensitivity reactions, review medication lists and counsel patients accordingly. This article is protected by copyright. All rights reserved.

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This article was published in the following journal.

Name: Photodermatology, photoimmunology & photomedicine
ISSN: 1600-0781
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