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Case Studies in Neuroscience: The electrophysiology of a human obsession in nucleus accumbens.

08:00 EDT 24th April 2019 | BioPortfolio

Summary of "Case Studies in Neuroscience: The electrophysiology of a human obsession in nucleus accumbens."

Microelectrode recordings were performed during awake deep brain stimulation surgery for obsessive-compulsive disorder, revealing robust brain oscillations that were plainly visible throughout the ventral striatum. There was an elegant topological correspondence between each oscillation and the underlying brain anatomy, most prominently a ~35Hz gamma-oscillation specific to the nucleus accumbens. Direct provocation of the patient's contamination obsession modulated both firing rate and gamma-oscillation amplitude within the nucleus accumbens.

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This article was published in the following journal.

Name: Journal of neurophysiology
ISSN: 1522-1598
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