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Novel statistical analyses to assess hearing outcomes following ABI implantation in NF2 patients: Systematic review and individualized patient data analysis.

08:00 EDT 3rd May 2019 | BioPortfolio

Summary of "Novel statistical analyses to assess hearing outcomes following ABI implantation in NF2 patients: Systematic review and individualized patient data analysis."

Patients with NF2 develop bilateral vestibular schwannomas with progressive hearing loss. Auditory brainstem implants (ABIs) stimulate hearing in the cochlear nuclei and show promise in improving hearing. Here, we assess the impact of ABI on hearing over time by systematically reviewing the literature and re-analyzed available individual patient data
METHODS:
A multidatabase search identified three studies with individual patient data of longitudinal hearing outcomes after ABI insertion in adults. Data was collected on hearing outcomes of different sound complexities from sound to speech using an ABI ± lip reading ability plus demographic data. Due to heterogeneity each study was analyzed separately using random effect multi-level mixed linear modelling.

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This article was published in the following journal.

Name: World neurosurgery
ISSN: 1878-8769
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