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Ageing characteristics of bone indicated by transcriptomic and exosomal proteomic analysis of cortical bone cells.

08:00 EDT 10th May 2019 | BioPortfolio

Summary of "Ageing characteristics of bone indicated by transcriptomic and exosomal proteomic analysis of cortical bone cells."

Degenerative changes in the skeleton play an important role in ageing. As the foremost sensors and orchestrators of bone remodelling, osteocytes contribute significantly to the health of the skeleton. Embedded in a mineralized bone matrix, the osteocyte network and the surrounding lacunar canaliculae work together as a functional syncytium-the osteocytic lacunar-canalicular system (OLCS). However, changes in the OLCS during ageing and related mechanisms cannot be fully understood by using traditional histological analysis.

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This article was published in the following journal.

Name: Journal of orthopaedic surgery and research
ISSN: 1749-799X
Pages: 129

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