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Radiosurgery for Chordoma and Chondrosarcoma.

08:00 EDT 16th May 2019 | BioPortfolio

Summary of "Radiosurgery for Chordoma and Chondrosarcoma."

Chordomas and chondrosarcomas are rare locally aggressive skull base tumors with high progression or recurrence rates. Ultimately, they have high mortality rates unless they respond to multimodality management options that include one or more surgical resections, fractionated radiation therapy, and stereotactic radiosurgery (SRS). SRS has become a standard management option for recurrent or residual chordomas and chondrosarcomas after failed surgical resection and fractionated radiation therapy. This report examines the role of SRS in these skull base tumors.

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Journal Details

This article was published in the following journal.

Name: Progress in neurological surgery
ISSN: 1662-3924
Pages: 207-214

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PubMed Articles [173 Associated PubMed Articles listed on BioPortfolio]

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Previous researches suggested microRNA-140-3p (miR-140-3p) and miR-155-5p as cancer promotor in chordoma. We aimed to investigate the mechanisms of these two miRNAs in chordoma cells. Patient-derived ...

Clinical Trials [212 Associated Clinical Trials listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)

A radiological stereotactic technique developed for cutting or destroying tissue by high doses of radiation in place of surgical incisions. It was originally developed for neurosurgery on structures in the brain and its use gradually spread to radiation surgery on extracranial structures as well. The usual rigid needles or probes of stereotactic surgery are replaced with beams of ionizing radiation directed toward a target so as to achieve local tissue destruction.

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