Potential for breath test diagnosis of urease positive pathogens in lung infections.

08:00 EDT 16th May 2019 | BioPortfolio

Summary of "Potential for breath test diagnosis of urease positive pathogens in lung infections."

Roles for urease in virulence are accepted for Helicobacter pylori and urinary tract pathogens. However, urease is widely expressed by bacterial and fungal lung pathogens causing emerging and opportunistic lung infections, organisms causing acute exacerbations of chronic bronchitis, mycobacterial lung diseases such as tuberculosis (TB), and ventilator associated pneumonia (VAP) and health care associated pneumonia (HAP). Detection of urease provides a method for rapid in vivo detection of these lung pathogens by inhaled 13C- breath test, and this review discusses the range of lung pathogens that might be amenable to rapid diagnosis.


Journal Details

This article was published in the following journal.

Name: Journal of breath research
ISSN: 1752-7163


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