Mechanical Insufflation/Exsufflation Improves Respiratory Mechanics In Critical Care: Randomized Crossover Trial.

08:00 EDT 13th May 2019 | BioPortfolio

Summary of "Mechanical Insufflation/Exsufflation Improves Respiratory Mechanics In Critical Care: Randomized Crossover Trial."

This study evaluated the ventilatory and haemodynamic effects of the mechanical insufflator-exsufflator (MI-E) in critically ill patients. Sixteen mechanically ventilated patients performed three protocols: MI-E (-30/+30 cmH2O) plus endotracheal suctioning; 50
MI-E (-50/+50 cmH2O) plus endotracheal suctioning; and isolated endotracheal suctioning (IES). The protocols were applied randomly in all subjects, with 3 -h intervals in between. Peak airway pressure (Ppeak), plateau pressure (Pplat), airway resistance (Raw), static compliance (Cst), heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure, peripheral oxygen saturation (SpO2) and amount of removed secretions were evaluated before (PRE), immediately after (POST) and 10 minutes after (10' POST) each protocol. The 50S protocol reduced Ppeak and Raw and increased Cst immediately after its application. Moreover, this protocol provided the largest amount of removed secretions and held SBP, DBP and SpO2 at basal values. The MI-E at high pressures promotes benefits to respiratory mechanics, is more effective in removing pulmonary secretions and it does not lead to hemodynamic repercussions.


Journal Details

This article was published in the following journal.

Name: Respiratory physiology & neurobiology
ISSN: 1878-1519


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