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Although the frequency of bone and joint infection caused by Enterobacter spp is increasing, studies regarding the optimal antibiotic therapy are scarce. The objective of the current retrospective study was to assess the clinical outcomes and safety of a fluoroquinolone-cotrimoxazole combination for the treatment of bone and joint infections caused by E. cloacae. Between 2010 and 2017, 30 patients with bone and joint infection caused by E. cloacae were treated with a fluoroquinolone-cotrimoxazole combination for 8 to 12 weeks. The type of infection was infection of an internal fixation device in 26 cases (87%), pseudarthrosis with chronic osteomyelitis in 2 cases (6.6%), and infection of knee and ankle prosthetic devices in 2 cases (6.6%). The cure rate of the fluoroquinolone-cotrimoxazole combination was 80% by intention-to-treat with a mean follow-up of 29.3± 19.1 months. The fluoroquinolone-cotrimoxazole combination for 8 to 12 weeks is effective for the treatment of bone and joint infection caused by E. cloacae.
This article was published in the following journal.
Name: International journal of antimicrobial agents
Enterobacteriaceae are recognized as leading pathogens of healthcare-associated infections. This is a report describing an investigation of a nosocomial outbreak of extended-spectrum ß-lactamase prod...
In Minnesota and North Dakota, a clonal strain of bla-producing Enterobacter cloacae complex has been reported with increasing frequency.
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To characterize an MDR blaIMP-4-harbouring plasmid from Enterobacter cloacae EC62 of swine origin in China.
In August 2015 seventeen neonates with Enterobacter (E.) cloacae colonisation were identified in a neonatal intensive care unit (NICU) in Germany. Two developed severe brain abscesses. Despite tempora...
The problem of interest is that we are looking for new antibiotic treatments for bone and joint infections. Treatment for bone and joint infection is not standardized, which allows a wide ...
Treatment of bone and joint infections remains difficult and variable according to centres and countries. Clindamycin given intravenously and followed by an oral route is recommended for t...
Daptomycin is a cyclic lipopeptide that has been proposed as an alternative therapeutic option in patients with prosthetic joint infection caused by Staphylococcus or Enterococcus species ...
Bone and joint infection (BJI) are bacterial infections that can occur after surgery (nosocomial infections) or de novo. They constitute a public health problem in Western Countries . Thes...
Cephamycin related to 2nd generation cephalosporins, the use of cefoxitin has long been limited to antibiotic prophylaxis. Because of its spectrum (sensitive staphylococci, enterobacteria ...
A species of gram-negative bacteria in the genus ENTEROBACTER, found in the environment and in foods. It has biochemical characteristics similar to ENTEROBACTER CLOACAE, but is yellow-pigmented.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in water, sewage, soil, meat, hospital environments, and on the skin and in the intestinal tract of man and animals as a commensal.
Gram-negative rods widely distributed in LIZARDS and SNAKES, and implicated in enteric, bone (BONE DISEASES), and joint infections (JOINT DISEASES) in humans.
The joint that is formed by the distal end of the RADIUS, the articular disc of the distal radioulnar joint, and the proximal row of CARPAL BONES; (SCAPHOID BONE; LUNATE BONE; triquetral bone).
Tearing away of the CORTICAL BONE fragment at the location of a strong ligament or tendon attachment. The bone fragment detachment site often occurs near a soft site (e.g., GROWTH PLATE) at the base where LIGAMENTS; TENDONS; or JOINT CAPSULES attach. In younger patients it is most often caused by a sudden forceful pull on a tendon in the opposite direction of the bone movement. In the elderly it is associated with osteoporotic INSUFFICIENCY FRACTURES.
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...
Arthritis Fibromyalgia Gout Lupus Rheumatic Rheumatology is the medical specialty concerned with the diagnosis and management of disease involving joints, tendons, muscles, ligaments and associated structures (Oxford Medical Diction...
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