Determining the Optimal Dose of Infliximab for Treatment of Hidradenitis Suppurativa.

08:00 EDT 13th May 2019 | BioPortfolio

Summary of "Determining the Optimal Dose of Infliximab for Treatment of Hidradenitis Suppurativa."

Little data exist guiding infliximab dosing in hidradenitis suppurativa (HS).


Journal Details

This article was published in the following journal.

Name: Journal of the American Academy of Dermatology
ISSN: 1097-6787


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Medical and Biotech [MESH] Definitions

A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident.

A treatment schedule in which the total dose of radiation is divided into large doses.

The inflammation of a sweat gland (usually of the apocrine type). The condition can be idiopathic or occur as a result of or in association with another underlying condition. Neutrophilic eccrine hidradenitis is a relatively rare variant that has been reported in patients undergoing chemotherapy, usually for non-Hodgkin lymphomas or leukemic conditions.

A chimeric monoclonal antibody to TNF ALPHA that is used in the treatment of RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; PSORIATIC ARTHRITIS and CROHN'S DISEASE.

The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

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An antibody is a protein produced by the body's immune system when it detects harmful substances, called antigens. Examples of antigens include microorganisms (such as bacteria, fungi, parasites, and viruses) and chemicals. Antibodies may be produc...

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