Calcitriol suppresses lipopolysaccharide-induced alveolar bone damage in rats by regulating T helper cell subset polarization.

08:00 EDT 16th May 2019 | BioPortfolio

Summary of "Calcitriol suppresses lipopolysaccharide-induced alveolar bone damage in rats by regulating T helper cell subset polarization."

Although the immunomodulatory properties of calcitriol in bone metabolism have been documented for decades, its therapeutic role in the management of periodontitis remains largely unexplored. In this study, we hypothesized that calcitriol suppresses lipopolysaccharide (LPS)-induced alveolar bone loss by regulating T helper (Th) cell subset polarization.


Journal Details

This article was published in the following journal.

Name: Journal of periodontal research
ISSN: 1600-0765


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Medical and Biotech [MESH] Definitions

Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.

Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE.

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The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).

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