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Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs.

08:00 EDT 16th May 2019 | BioPortfolio

Summary of "Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs."

Primary hepatic angiosarcoma is a rare tumor with poor prognosis. The aim of this study was to generate a new angiosarcoma model to improve research on hepatic angiosarcoma.

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Journal Details

This article was published in the following journal.

Name: PloS one
ISSN: 1932-6203
Pages: e0214756

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Medical and Biotech [MESH] Definitions

A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.

A drug-metabolizing enzyme of the hepatic microsomal oxidase system which catalyzes the oxidation of the N-methyl group of ethylmorphine with the formation of formaldehyde.

Cholangiocarcinoma arising near or at the confluence of the right and left hepatic ducts (COMMON HEPATIC DUCT). These tumors are generally small, sharply localized, and seldom metastasizing.

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A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.

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