Advertisement

Topics

Principal Component Analysis Based Dynamic Cone Beam X-Ray Luminescence Computed Tomography: A Feasibility Study.

08:00 EDT 15th May 2019 | BioPortfolio

Summary of "Principal Component Analysis Based Dynamic Cone Beam X-Ray Luminescence Computed Tomography: A Feasibility Study."

Cone beam X-ray luminescence computed tomography (CB-XLCT) is a promising imaging technique in studying the physiological and pathological processes in small animals. However, the dynamic bio-distributions of probes in small animal especially in adjacent targets are still hard to be captured directly from dynamic CB-XLCT. In this work, a 4D temporal-spatial reconstruction method based on principal component analysis (PCA) in the projection space is proposed for dynamic CB-XLCT. Firstly, projections of angles in each 3D frame are compressed to reduce the noises initially. Then a temporal PCA is performed on the projection data to decorrelate the 4D problem into separate 3D problems in the PCA domain. In the PCA domain, the difference between dynamic behaviors of multiple targets can be reflected by the first several principal components which can be further used for fast and improved reconstruction by a restarted Tikhonov regularization method. At last, by discarding the principal components mainly reflecting noise, the concentration series of targets are recovered from the first few reconstruction results with a mask as the constraint. Numerical simulation and phantom experiment demonstrate that the proposed method can resolve multiple targets and recover the dynamic distributions with high computation efficiency. The proposed method provides a new feasibility for imaging dynamic bio-distributions of probes in vivo.

Affiliation

Journal Details

This article was published in the following journal.

Name: IEEE transactions on medical imaging
ISSN: 1558-254X
Pages:

Links

DeepDyve research library

PubMed Articles [31066 Associated PubMed Articles listed on BioPortfolio]

Cherenkov-excited luminescence scanned imaging using scanned beam differencing and iterative deconvolution in dynamic plan radiation delivery in a human breast phantom geometry.

The purpose of this study was to demonstrate high resolution optical luminescence sensing, referred to as Cherenkov excited luminescence scanning imaging (CELSI), could be achieved during a standard d...

A significant incidental finding on cone beam computed tomography: multiple myeloma.

Cone beam computed tomography is widely used in dentistry. Incidental findings are common, with many requiring intervention or monitoring. We present a rare case of previously undiagnosed, asymptomati...

Dimensional accuracy of cone beam CT with varying angulation of the jaw to the X-ray beam.

Cone beam CT (CBCT) machines do not always allow for patients to be scanned in the ideal position for image acquisition. This study aimed to investigate the influence of the position/angulation of the...

A novel image-based retrieval system for characterization of maxillofacial lesions in cone beam CT images.

The objective of medical content-based image retrieval (CBIR) is to assist clinicians in decision making by retrieving the most similar cases to a given query image from a large database. Herein, a ne...

Detection and location of second mesiobuccal canal in permanent maxillary teeth: A cone-beam computed tomography analysis in a Taiwanese population.

The aim of this study was to analyze the incidence, symmetry, concurrence of second mesiobuccal canal (MB2) and determine geometric relationships between each orifice of maxillary first and second mol...

Clinical Trials [6962 Associated Clinical Trials listed on BioPortfolio]

Interest of the Cone-beam Computed Tomography in the Imagery of the Middle Ear

Cone beam computed tomography (CBCT), is a recent medical imaging technique where the X-rays are divergent, forming a cone. As a result, this technique is less irradiating that the scanne...

Cone Beam Computed Tomography (CT) Bladder

This study is designed to investigate whether daily images of the pelvis and bladder using a device called a cone beam CT scanner will help to increase the accuracy of radiotherapy treatme...

Use of Cone Beam Kilovaltage Imaging in Patients Receiving Radiation Therapy for Head and Neck Cancer

To evaluate the use of cone beam computed tomography in treating head and neck to hopefully reduce side effects

Multiple Respiration-Correlated Cone Beam Computed Tomography (CT) Scans to Reduce Target Positioning Errors in Radiotherapy Treatment of Thoracic Cancer

The purpose of this study is to use cone-beam CT scans to more accurately position the tumor during radiation and to see whether this method is more effective than the standard method of u...

C-arm Cone Beam CT Perfusion Guided Cerebrovascular Interventions

The overarching objective of our proposal is to develop a One-Stop-Shop imaging using the available C-arm Cone-Beam Computed Tomography (CBCT) data acquisition systems currently widely ava...

Medical and Biotech [MESH] Definitions

Modality of computed tomography in which the patient is irradiated in a spiral path around the body with a cone or pyramid-shaped beam.

Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.

Photosensitive proteins expressed in the CONE PHOTORECEPTOR CELLS. They are the protein components of cone photopigments. Cone opsins are classified by their peak absorption wavelengths.

A method of chemical analysis based on the detection of characteristic radionuclides following a nuclear bombardment. It is also known as radioactivity analysis. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

The science and application of a double-beam transmission interference microscope in which the illuminating light beam is split into two paths. One beam passes through the specimen while the other beam reflects off a reference mirror before joining and interfering with the other. The observed optical path difference between the two beams can be measured and used to discriminate minute differences in thickness and refraction of non-stained transparent specimens, such as living cells in culture.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topic

Radiology
Radiology is the branch of medicine that studies imaging of the body; X-ray (basic, angiography, barium swallows), ultrasound, MRI, CT and PET. These imaging techniques can be used to diagnose, but also to treat a range of conditions, by allowing visuali...


Searches Linking to this Article