Characterizing the fluctuations of dynamic resting-state electrophysiological functional connectivity: Reduced neuronal coupling variability in mild cognitive impairment and dementia due to Alzheimer's disease.

08:00 EDT 21st May 2019 | BioPortfolio

Summary of "Characterizing the fluctuations of dynamic resting-state electrophysiological functional connectivity: Reduced neuronal coupling variability in mild cognitive impairment and dementia due to Alzheimer's disease."

The characterization of brain functional connectivity is a helpful tool in the study of the neuronal substrates and mechanisms that are altered in Azheimer's Disease (AD) and mild cognitive impairment (MCI). Recently, there has been a shift towards the characterization of dynamic functional connectivity (dFC), discarding the assumption of connectivity stationarity during the resting-state. The majority of these studies have been performed with functional magnetic resonance imaging (fMRI) recordings, with only a small subset being based on magnetoencephalography/electroencephalography (MEG/EEG). However, only these modalities enable the characterization of potentially fast brain dynamics, which is mandatory for an accurate understanding of the transmission and processing of neuronal information. The aim of this study was to characterize the dFC of resting-state EEG activity in AD and MCI.


Journal Details

This article was published in the following journal.

Name: Journal of neural engineering
ISSN: 1741-2552


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