Reasons for successful clinical outcome following pulmonary vein isolation despite lack of persistent LA-PV conduction block.

08:00 EDT 22nd May 2019 | BioPortfolio

Summary of "Reasons for successful clinical outcome following pulmonary vein isolation despite lack of persistent LA-PV conduction block."

The mechanisms of AF induction and maintenance, including those involved in paroxysmal atrial fibrillation, are not completely known; this limits our ablation strategies and prevents us from understanding what we are actually doing when performing pulmonary vein isolation. In this report, we focus on the commonly used ablation strategies for atrial fibrillation and question the importance of complete pulmonary vein isolation in achieving lasting success in the ablation of atrial fibrillation. We also discuss in detail the absence of durable pulmonary vein isolation in patients without arrhythmic recurrences after atrial fibrillation ablation and the possibility to cure paroxysmal atrial fibrillation without concomitant pulmonary vein isolation, provocatively questioning the dogma of pulmonary vein isolation as the cornerstone of atrial fibrillation ablation. Finally, a prospective personalized approach in the individual patient is advocated. This article is protected by copyright. All rights reserved.


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This article was published in the following journal.

Name: Pacing and clinical electrophysiology : PACE
ISSN: 1540-8159


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Medical and Biotech [MESH] Definitions

Narrowing of the PULMONARY VEIN.

An anomalous pulmonary venous return in which the right PULMONARY VEIN is not connected to the LEFT ATRIUM but to the INFERIOR VENA CAVA. Scimitar syndrome is named for the crescent- or Turkish sword-like shadow in the chest radiography and is often associated with hypoplasia of the right lung and right pulmonary artery, and dextroposition of the heart.

A malformation of the heart in which the embryonic common PULMONARY VEIN was not incorporated into the LEFT ATRIUM leaving behind a perforated fibromuscular membrane bisecting the left atrium, a three-atrium heart. The opening between the two left atrium sections determines the degree of obstruction to pulmonary venous return, pulmonary venous and pulmonary arterial hypertension.

A short thick vein formed by union of the superior mesenteric vein and the splenic vein.

Placement of a balloon-tipped catheter into the pulmonary artery through the antecubital, subclavian, and sometimes the femoral vein. It is used to measure pulmonary artery pressure and pulmonary artery wedge pressure which reflects left atrial pressure and left ventricular end-diastolic pressure. The catheter is threaded into the right atrium, the balloon is inflated and the catheter follows the blood flow through the tricuspid valve into the right ventricle and out into the pulmonary artery.

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