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Genome-wide DNA methylation profile in the peripheral blood of cocaine and crack dependents.

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Summary of "Genome-wide DNA methylation profile in the peripheral blood of cocaine and crack dependents."

Cocaine use disorders (CUDs) represent a major public health problem in many countries. To better understand the interaction between the environmental modulations and phenotype, the aim of the present study was to investigate the DNA methylation pattern of CUD patients, who had concomitant cocaine and crack dependence, and healthy controls.

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This article was published in the following journal.

Name: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
ISSN: 1809-452X
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The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.

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