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The large water holding capacity of Basil Seed (Ocimum basilicum L.) Mucilage (BSM) gives it potential to produce a valuable polymer for water holding applications such as wound dressing. The objective of this research was to prepare a natural-based antibacterial wound dressing from BSM by freeze-drying. Various contents of zinc oxide nanoparticles (ZnO-NP) were incorporated as an antibacterial agent. BSM hydrogel sponge showed considerable porosity and degree of swelling. From FTIR analysis, hydrogen bond and electrostatic interaction between BSM molecules and ZnO-NP were confirmed. SEM images revealed an interconnecting open-cell structure of pores in the BSM hydrogel sponge with a good distribution of ZnO-NP. Moreover, increase in ZnO-NP content improved the mechanical properties (stress at maximum load 8.9 MPa, Young's modulus 151 MPa and strain at maximum load 51%), thermal properties, water retention capacity and antibacterial activity. Cytotoxicity and cell adhesion studies of BSM hydrogel sponge indicated non-cytotoxicity and non-adherent nature of the sponge.
This article was published in the following journal.
Name: International journal of biological macromolecules
An attempt was made to formulate moxifloxacin loaded alginate beads incorporated into spongy wound dressing to heal chronic wounds as well as to reduce frequency of painful dressing change. Moxifloxac...
Dressing is an essential element of standard wound care. The main purpose of wound dressing is: a) provide a temporary protective physical barrier, b) absorb wound drainage, and c) provide the moistur...
Fabrication of an antibiotic-loaded scaffold with controlled release properties for wound dressing is one of tissue engineering challenges. The aim of this study was to evaluate the wound-healing effe...
Wound dressings with antimicrobial and wound healing accelerating properties are emerging as valuable options to prevent wound infection and improve the wound healing process. In this study, high poro...
We determined whether 5 common essential oils (basil, fennel seed, orange, black pepper and sage) interfered with feto-placental steroidogenesis in a co-culture model composed of fetal-like adrenocort...
The purpose of this study is to determine whether a bioelectric wound dressing, a silver-coated dressing, or a silver-foam dressing are effective in the treatment of wounds resulting from ...
This randomized, prospective study evaluates incision closure, post-surgical wound complications, dressing changes, incision/scar appearance, pain associated with dressing changes, and pat...
This is a study comparing two methods of dressing a post operative wound that are currently in practice. One method is a traditional dry gauze dressing. The other method is using a negativ...
The study is a prospective randomised, controlled study of 136 patients undergoing vascular surgery. Their closed wounds were covered with either aquacel, a hydrofiber dressing, or a tradi...
This is a prospective randomized study evaluating the use of a prophylactic incision wound vac dressing, applied in the OR, on patients undergoing posterior spine surgery with a BMI>35. Pa...
A plant genus of the family Lamiaceae which occurs in tropical and warm temperate regions worldwide. It includes the aromatic herb OCIMUM BASILICUM (Sweet Basil) and the MEDICINAL PLANT Ocimum tenuiflorum (Holy Basil).
The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.
A plant species of the genus OCIMUM, family LAMIACEAE that has been used in TRADITIONAL MEDICINE.
A plant species of the genus OCIMUM, family LAMIACEAE. It is a condiment with carminative properties.
Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...
Stress is caused by your perception of situations around you and then the reaction of your body to them. The automatic stress response to unexpected events is known as 'fight or flight'. Discovered by Walter Cannon in 1932, it is the release of h...