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Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus.

08:00 EDT 31st May 2019 | BioPortfolio

Summary of "Highly oxygenated meroterpenoids from the Antarctic fungus Aspergillus terreus."

Eleven highly oxygenated meroterpenoids, named terreustoxins A-K, along with five known analogues, were isolated from the Antarctic fungus Aspergillus terreus. The structures and absolute configurations of these undescribed compounds were characterized by NMR spectroscopy, single-crystal X-ray crystallography, and ECD experiments. Terreustoxins A-D are the first examples of meroterpenoids with two ortho-hydroxy groups at C-6 and C-7 in the terretonins family. Terreustoxin C and terretonin inhibited the proliferation of Con A-induced murine T cells at the concentration of 10 μM.

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This article was published in the following journal.

Name: Phytochemistry
ISSN: 1873-3700
Pages: 184-191

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