Inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients.

08:00 EDT 7th June 2019 | BioPortfolio

Summary of "Inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients."

Acne is the most common inflammatory skin disease, affecting up to 85% of the 11-30 years old world population. Skin microbiota appears as a key player involved in several skin dermatoses physiopathology. Here, we show that inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients but also on the face of patients where acne was scored as mild to moderate, comparing with healthy controls. Changes were observed particularly on skin commensals Propionibacteriaceae, Staphylococcaceae and Enterococcaceae families, suggesting the importance of the balance between skin commensals to maintain skin homeostasis and control skin inflammatory process. This article is protected by copyright. All rights reserved.


Journal Details

This article was published in the following journal.

Name: Experimental dermatology
ISSN: 1600-0625


DeepDyve research library

PubMed Articles [9628 Associated PubMed Articles listed on BioPortfolio]

Revealing the secret life of skin With the microbiome you never walk alone.

The human skin microbiome has recently become a focus for both the dermatological and cosmetic fields. Understanding the skin microbiota, i.e. the collection of vital microorganisms living on our skin...

Staphylococcus epidermidis role in the skin microenvironment.

Wound healing is a complex dynamic physiological process in response to cutaneous destructive stimuli that aims to restore the cutaneous' barrier role. Deciphering the underlying mechanistic details t...

Targeting the gut-skin axis - probiotics as new tools for skin disorder management?

The existence of a gut-skin axis is supported by increasing evidence, but its translational potential is not widely recognized. Studies linked inflammatory skin diseases to an imbalanced gut microbiom...

Insight into the redox status of inflammatory skin equivalents as determined by EPR spectroscopy.

Atopic dermatitis (AD) is a chronic inflammatory skin disease whose pathogenesis is still not fully understood. Since inflammatory processes correlate with oxidative stress, the redox status may play ...


Manipulating intestinal microbiota with probiotics might stimulate skin response. Understanding all stages of the healing process, as well as the gut-skin-healing response can improve the skin healing...

Clinical Trials [8650 Associated Clinical Trials listed on BioPortfolio]

Survey of the Facial Bacteriome

The microbiome can affect skin health from the gut-skin axis, from environmental exposure, and topical treatments. Decreasing biodiversity of skin microbiota has been linked to inflammator...

Identification of the Cutaneous Microbiota in Patients With Cutaneous Infection (MICROBIOTA)

Identify the cutaneous microbiota on a cutaneous lesion (cellulite, wound, rash, etc.) on a swab, biopsies or abscess puncture and on "healthy" skin on a skin swab performed for cutaneous ...

Characterization of Cutaneous Microbiota in the Psoriasis Pathogenesis

The skin harbors a complex and dynamic microbiota constituted by numerous microorganisms that live in symbiosis with the host. The specific etiology of psoriasis is still not-well understo...

Methods Validation Assessment for Study of Inflammatory Skin Disease

1. Assess validity of methods involved in molecular studies of the skin in inflammatory skin disease 2. Assess feasibility of methods for grafting fresh human skin (normal and dise...

UVB: Skin to Gut Study

This research will explore the potential effects of Narrow-Band Ultra Violet B (NB-UVB) radiation on the intestinal microbiota composition and confirm a regulatory skin-to-gut axis during ...

Medical and Biotech [MESH] Definitions

The functions of the skin in the human and animal body. It includes the pigmentation of the skin.

The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.

Skin lumpiness or skin surface dimpling often seen on the thighs, buttocks and abdomen. It is due to protrusion of SUBCUTANEOUS FAT into the DERMIS layer of skin.

Maintenance of the hygienic state of the skin under optimal conditions of cleanliness and comfort. Effective in skin care are proper washing, bathing, cleansing, and the use of soaps, detergents, oils, etc. In various disease states, therapeutic and protective solutions and ointments are useful. The care of the skin is particularly important in various occupations, in exposure to sunlight, in neonates, and in PRESSURE ULCER.

Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.

Quick Search

DeepDyve research library

Relevant Topics

Acne Dermatology Eczema Psoriasis Wound Care Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary). As well as studying how the skin works, dermatology covers...

Wound management
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...

Acne is a common skin condition that causes spots to develop on the skin, usually on the face, back and chest..  The spots can range from blackheads and whiteheads which are often mild, to inflamed pus-filled pustules and cysts, which can be severe ...

Searches Linking to this Article