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Measurement of Specific IgG Anti-Fel d 1 Antibodies.

07:00 EST 1st January 2019 | BioPortfolio

Summary of "Measurement of Specific IgG Anti-Fel d 1 Antibodies."

There is currently considerable interest in the role of specific IgG antibodies in allergy. Several studies suggest that specific IgG antibodies may play a protective role in allergy. Successful immunotherapy is associated with increases in allergen-specific IgG antibodies which correlate with clinical outcome. Other studies have identified an inverse relationship between exposure to cat and sensitization, which was associated with high-titer-specific IgG and IgG. This immune response was described as a modified Th2 response, since both IgE and IgG require Th2 cytokine IL-4 for their production. A modified Th2 response was described with laboratory animal allergy, where there was almost a twofold reduction in the risk of developing work-related chest symptoms.In this chapter, we review the major factors to be considered in the development of an ELISA for the determination of specific IgG and IgG antibodies.

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This article was published in the following journal.

Name: Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Pages: 207-214

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