Advertisement

Topics

Counteracting sarcopenia: the role of IGF-1 isoforms.

08:00 EDT 13th June 2019 | BioPortfolio

Summary of "Counteracting sarcopenia: the role of IGF-1 isoforms."

No Summary Available

Affiliation

Journal Details

This article was published in the following journal.

Name: Aging
ISSN: 1945-4589
Pages:

Links

DeepDyve research library

PubMed Articles [9142 Associated PubMed Articles listed on BioPortfolio]

Effects of IGF-1 isoforms on muscle growth and sarcopenia.

The decline in skeletal muscle mass and strength occurring in aging, referred as sarcopenia, is the result of many factors including an imbalance between protein synthesis and degradation, changes in ...

The role of sarcopenia in patients with intrahepatic cholangiocarcinoma: Prognostic marker or hyped parameter?

Sarcopenia has emerged as a prognostic parameter in numerous cancer entities. Current research favours its role as a determining factor for overall survival (OS) in patients with intrahepatic cholangi...

Gait speed as a mediator of the effect of sarcopenia on dependency in activities of daily living.

Sarcopenia in older adults is strongly associated with an increase in dependency in activities of daily living (ADL) and with a decline in gait speed. Interestingly, gait speed has been shown to indep...

The Influence of Sarcopenia on High-Risk Neuroblastoma.

Sarcopenia is a syndrome that is defined by the loss of skeletal muscle mass, quality, and strength. In adult patients with malignancies, the presence of sarcopenia is known to be correlated with a po...

4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia.

Sarcopenia is the loss of muscle mass/function that occurs during the aging process. The links between mechanistic target of rapamycin (mTOR) activity and muscle development are largely documented, bu...

Clinical Trials [2294 Associated Clinical Trials listed on BioPortfolio]

Measurement of Different Anti-Müllerian Hormone Isoforms in Expected Poor Responders

This study wants to evaluate significant clinical impact of different AMH isoforms in serum can be present or absent in expected poor responder patients. The specific AMH isoforms could th...

Could a Preoperative Feeding Jejunostomy Decrease Sarcopenia for Patients With Oesogastric Adenocarcinoma ?

The study of sarcopenia is a subject that is the subject of numerous research and publications, particularly because of its link with a poor prognosis for many cancers. In an article publ...

Role of MicroRNAs on Age and Contraction-induced Skeletal Muscle Growth

Sarcopenia is a predictor of functional-limitation, leading to loss of independence, lowered quality of life, and ultimately death. The impaired ability of aged skeletal muscle to adapt to...

Nutritional Intervention for Sarcopenia

Sarcopenia is an age-related poor healthy outcome. nutrition intervention is one , progressive, generalized loss of muscle mass and the decrement in physical activity. Sarcopenia is associ...

Clinical Trial to Assess the Preventive Effects of Cetylpyridinium Chloride on Sarcopenia

This study is to assess the impact on the prevention of sarcopenia after taking cetylpyridinium chloride targeting the patients of pre-sarcopenia or sarcopenia over the age of 60

Medical and Biotech [MESH] Definitions

Agents counteracting or neutralizing the action of POISONS.

Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.

Transmembrane proteins belonging to the tumor necrosis factor superfamily that play an essential role in the normal development of several ectodermally derived organs. Several isoforms of the ectodysplasins exist due to multiple ALTERNATIVE SPLICING of the MRNA for the protein. The isoforms ectodysplasin A1 and ectodysplasin A2 are considered biologically active and each bind distinct ECTODYSPLASIN RECEPTORS. Genetic mutations that result in loss of function of ectodysplasin result in ECTODERMAL DYSPLASIA 1, ANHIDROTIC.

A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regulatory subunits. At least two genes encode isoforms of the protein phosphatase catalytic subunit, while several isoforms of regulatory subunits exist due to the presence of multiple genes and the alternative splicing of their mRNAs. Protein phosphatase 2 acts on a broad variety of cellular proteins and may play a role as a regulator of intracellular signaling processes.

A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article