Advertisement

Topics

Perylene-functionalized graphene sheets modified with β-cyclodextrin for the voltammetric discrimination of phenylalanine enantiomers.

08:00 EDT 4th June 2019 | BioPortfolio

Summary of "Perylene-functionalized graphene sheets modified with β-cyclodextrin for the voltammetric discrimination of phenylalanine enantiomers."

A facile approach was reported to synthesize β-cyclodextrin functionalized graphene that is bridged by 3,4,9,10-perylene tetracarboxylic acid (rGO-PTCA-CD) via a chemical route that involves the functionalization of rGO with PTCA followed by covalently cross-linking NH-β-CD. The as-prepared rGO-PTCA-CD was characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, X-ray photoelectron spectroscopy and electrochemical methods. The working electrodes were thoroughly studied for the cyclic voltammetry by using [Fe(CN)] as redox probe and using ferrocene as an internal standard. Furthermore, rGO-PTCA-CD was successfully applied to the recognition of phenylalanine enantiomers. The host-guest inclusion interaction between rGO-PTCA-CD and the phenylalanine enantiomers was investigated by differential pulse voltammetry with Fc used as a competitor. The recognition result showed that the rGO-PTCA-CD-modified glassy carbon electrode exhibited higher chiral recognition capability for L-Phe than for D-Phe with an enantioselectivity coefficient of 2.07. The proposed modified electrode had a limit of detection of 0.08 nM and 0.2 nM (S/N = 3) for L-Phe and D-Phe, respectively, with a linear response range of 0.01 mM to 5 mM, which was ascribed to the synergy of the rGO-PTCA (e.g., its excellent electrochemical performance) and β-CD (e.g., the hydrophobic inner cavity with good molecular recognition and enrichment abilities).

Affiliation

Journal Details

This article was published in the following journal.

Name: Bioelectrochemistry (Amsterdam, Netherlands)
ISSN: 1878-562X
Pages: 189-198

Links

DeepDyve research library

PubMed Articles [5287 Associated PubMed Articles listed on BioPortfolio]

A screen printed carbon electrode modified with a lamellar nanocomposite containing dendritic silver nanostructures, reduced graphene oxide, and β-cyclodextrin for voltammetric sensing of nitrite.

A disposable sensor is described for the determination of nitrite. A screen printed carbon electrode (SPCE) was modified with a 3D lamellar nanocomposite prepared by one-step electrodeposition from de...

Synergistic effect of a cobalt fluoroporphyrin and graphene oxide on the simultaneous voltammetric determination of catechol and hydroquinone.

Graphene oxide (GO) was modified with the cobalt(II) and zinc(II) complexes (CoTFPP and ZnTFPP) of 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin in order to improve the electrocatalytic activity of ...

Simultaneous voltammetric sensing of levodopa, piroxicam, ofloxacin and methocarbamol using a carbon paste electrode modified with graphite oxide and β-cyclodextrin.

A carbon paste electrode (CPE) was modified with graphite oxide (GrO) and β-cyclodextrin (CD) to obtain a sensor for simultaneous voltammetric determination of levodopa (LD), piroxicam (PRX), ofloxac...

Modified graphene/polyimide composite films with strongly enhanced thermal conductivity.

With the development of portable electronic devices, highly efficient thermal management has become an important design consideration which requires good flexibility and excellent thermal conductivity...

Graphene-ferrocene functionalized cyclodextrin composite with high electrochemical recognition capability for phenylalanine enantiomers.

Graphene oxide (GO) modified with ferrocene (Fc) was successfully assembled via the π-π interaction (GO-Fc) and had the features of large surface area and high loading. Then, a novel composite was s...

Clinical Trials [1552 Associated Clinical Trials listed on BioPortfolio]

Determining Lipid Content in Stool After Alpha-cyclodextrin

The Investigator hypothesizes that the currently used dose of dietary ingredient alpha-cyclodextrin (α-CD) will result in greater loss of dietary fat in the stool compared with placebo. T...

Study of 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) to Treat Niemann-Pick Type C1 (NPC1) Disease

This study evaluates the efficacy and safety of 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) in patients with neurologic manifestations of Niemann-Pick Type C1 (NPC1) Disease. Approximately ...

Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer

This randomized phase II trial studies how well giving topotecan hydrochloride or cyclodextrin-based polymer-camptothecin CRLX101 works in treating patients with recurrent small cell lung ...

This Study Assesses the Impact of Different Sheets on Body Temperature and Sleep

Thermal comfort and subsequent sleep quality will improve with the use of bedding that incorporates thermoregulation technology, in comparison to standard bedding products.

Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office Bleaching

Objectives: This study aims to evaluate the effectiveness of preemptive administration of non-steroidal anti-inflammatory Piroxicam-beta-Cyclodextrin on risk and level of tooth sensitivity...

Medical and Biotech [MESH] Definitions

Derivative of beta-cyclodextrin that is used as an excipient for steroid drugs and as a lipid chelator.

Food derived from genetically modified organisms (ORGANISMS, GENETICALLY MODIFIED).

A 20-carbon dibenz(de,kl)anthracene that can be viewed as a naphthalene fused to a phenalene or as dinaphthalene. It is used as fluorescent lipid probe in the cytochemistry of membranes and is a polycyclic hydrocarbon pollutant in soil and water. Derivatives may be carcinogenic.

An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.

A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topic

Radiology
Radiology is the branch of medicine that studies imaging of the body; X-ray (basic, angiography, barium swallows), ultrasound, MRI, CT and PET. These imaging techniques can be used to diagnose, but also to treat a range of conditions, by allowing visuali...


Searches Linking to this Article