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Activation of Ca1.2 and BK is involved in the downregulation of caffeine-induced contraction in mice mesenteric arteries.

08:00 EDT 10th June 2019 | BioPortfolio

Summary of "Activation of Ca1.2 and BK is involved in the downregulation of caffeine-induced contraction in mice mesenteric arteries."

Caffeine is a methylxanthine with multiple actions in vascular smooth muscle cells (VSMCs), including the increase in the intracellular Ca (Ca) concentration by the activation of ryanodine receptors (RyRs). The present study aimed at investigating the participation of Ca-influx through different Ca-channels on the transient contraction (TC) induced by caffeine in mice mesenteric arteries.

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Name: Life sciences
ISSN: 1879-0631
Pages: 116555

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