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Percutaneous sensitization is limited by in situ inhibition of cutaneous dendritic cell migration via skin-resident regulatory T cells.

08:00 EDT 10th June 2019 | BioPortfolio

Summary of "Percutaneous sensitization is limited by in situ inhibition of cutaneous dendritic cell migration via skin-resident regulatory T cells."

Percutaneous sensitization is associated with various allergic diseases, including asthma and food allergies. However, the immunological mechanisms underlying how the skin regulates percutaneous sensitization is still unclear.

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This article was published in the following journal.

Name: The Journal of allergy and clinical immunology
ISSN: 1097-6825
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Medical and Biotech [MESH] Definitions

Percutaneous excision of a herniated or displaced intervertebral disk by posterolateral approach, always remaining outside the spinal canal. Percutaneous nucleotomy was first described by Hijikata in Japan in 1975. In 1985 Onik introduced automated percutaneous nucleotomy which consists in percutaneous aspiration of the nucleus pulposus. It is carried out under local anesthesia, thus reducing the surgical insult and requiring brief hospitalization, often performed on an outpatient basis. It appears to be a well-tolerated alternative to surgical diskectomy and chymopapain nucleolysis.

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Non-hematopoietic cells, with extensive dendritic processes, found in the primary and secondary follicles of lymphoid tissue (the B cell zones). They are different from conventional DENDRITIC CELLS associated with T-CELLS. They are derived from MESENCHYMAL STEM CELLS and are negative for class II MHC antigen and do not process or present antigen like the conventional dendritic cells do. Instead, follicular dendritic cells have FC RECEPTORS and C3B RECEPTORS that hold antigen in the form of ANTIGEN-ANTIBODY COMPLEXES on their surfaces for long periods for recognition by B-CELLS.

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