Osmotic and Nonosmotic Sodium Storage during Acute Hypertonic Sodium Loading.

08:00 EDT 19th June 2019 | BioPortfolio

Summary of "Osmotic and Nonosmotic Sodium Storage during Acute Hypertonic Sodium Loading."

The Edelman equation has long guided the expected response of plasma [Na+] to changes in sodium, potassium, and water balance, but recent short-term studies challenged its validity. Plasma [Na+] following hypertonic NaCl infusion in individuals on low-sodium diet fell short of the Edelman predictions supposedly because sodium restriction caused progressive osmotic inactivation of 50% of retained sodium. Here, we examine the validity of this challenge.


Journal Details

This article was published in the following journal.

Name: American journal of nephrology
ISSN: 1421-9670
Pages: 1-8


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