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Analysis of patient-specific stimulation with segmented leads in the subthalamic nucleus.

08:00 EDT 19th June 2019 | BioPortfolio

Summary of "Analysis of patient-specific stimulation with segmented leads in the subthalamic nucleus."

Segmented deep brain stimulation leads in the subthalamic nucleus have shown to increase therapeutic window using directional stimulation. However, it is not fully understood how these segmented leads with reduced electrode size modify the volume of tissue activated (VTA) and how this in turn relates with clinically observed therapeutic and side effect currents. Here, we investigated the differences between directional and omnidirectional stimulation and associated VTAs with patient-specific therapeutic and side effect currents for the two stimulation modes.

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This article was published in the following journal.

Name: PloS one
ISSN: 1932-6203
Pages: e0217985

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Medical and Biotech [MESH] Definitions

Lens-shaped structure on the inner aspect of the internal capsule. The subthalamic nucleus and pathways traversing this region are concerned with the integration of somatic motor function. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p52)

The development and application of computational models of human pathophysiology that are individualized to patient-specific data.

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Moving a patient into a specific position or POSTURE to facilitate examination, surgery, or for therapeutic purposes.

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