A systematic review of the genetic mechanisms of dolutegravir resistance.

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Summary of "A systematic review of the genetic mechanisms of dolutegravir resistance."

Characterizing the mutations selected by the integrase strand transfer inhibitor (INSTI) dolutegravir and their effects on susceptibility is essential for identifying viruses less likely to respond to dolutegravir therapy and for monitoring persons with virological failure (VF) on dolutegravir therapy.


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This article was published in the following journal.

Name: The Journal of antimicrobial chemotherapy
ISSN: 1460-2091


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Medical and Biotech [MESH] Definitions

Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.

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