Topics

Reforming the Orphan Drug Act for the 21st Century.

08:00 EDT 11th July 2019 | BioPortfolio

Summary of "Reforming the Orphan Drug Act for the 21st Century."

No Summary Available

Affiliation

Journal Details

This article was published in the following journal.

Name: The New England journal of medicine
ISSN: 1533-4406
Pages: 106-108

Links

DeepDyve research library

PubMed Articles [7928 Associated PubMed Articles listed on BioPortfolio]

The Impact of the Orphan Drug Act on FDA-Approved Therapies for Rare Skin Diseases and Skin-Related Cancers.

The Orphan Drug Act of 1983 (ODA) put in place a set of financial and marketing incentives to stimulate the development of drugs to treat rare diseases, and since its passage more than 600 orphan drug...

Thermodynamic modelling and optimization of oxy-reforming and oxy-steam reforming of biogas by RSM.

In this study, a comparative thermodynamic equilibrium calculation of biogas oxy-reforming and oxy-steam reforming processes to produce syngas has been conducted by Aspen Plus simulation software. The...

Drug Development for Rare Paediatric Epilepsies: Current State and Future Directions.

Rare diseases provide a challenge in the evaluation of new therapies. However, orphan drug development is of increasing interest because of the legislation enabling facilitated support by regulatory a...

Impacts of climate change on snow accumulation and melting processes over mountainous regions in Northern California during the 21st century.

A point-location-based analysis of future climate change impacts on snow accumulation and melting processes was conducted over three study watersheds in Northern California during a 90-year future per...

Bringing Lymphangiography into the 21st Century.

Clinical Trials [2857 Associated Clinical Trials listed on BioPortfolio]

Estrogen and Diabetes

Diabetes has recently been referred to as "the epidemic of the 21st century". The reason why women with type 1 diabetes have a 2-3 fold greater risk of cardiovascular disease (CVD) compare...

High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour in Obese Women

Obesity is one of the biggest public health problems of the 21st century as it increases the risk of many co-morbid medical conditions. Obesity in pregnancy places women at higher risk of ...

Healthy Summer Learners

Summer vacation represents a "window of vulnerability" where dramatic declines in both health and academics occur for elementary age children. Currently, there are no summer programs that ...

Oral Health Status and Diet History Analysis Among Orphan House Children From 10-14 Years in Cairo Governorate.

the purpose of study to determine oral health status and dietary habits among group of orphan children from 10-14 years in Cairo Governorate.

The Importance of Exercise to Prevent Injuries in Athletes

Introduction: running is one of the most accessible and practiced sports in the world since the 21st century. Unfortunately, the incidence of injuries in the population that practices it i...

Medical and Biotech [MESH] Definitions

Time period from 2001 through 2100 of the common era.

A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 7 and neuraminidase 2. It has been involved in a number of outbreaks in the 21st century on poultry farms and has been isolated a few times in humans.

An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.

A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.

Production of drugs or biologicals which are unlikely to be manufactured by private industry unless special incentives are provided by others.

Quick Search


DeepDyve research library

Relevant Topic

Pharmacy
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...


Searches Linking to this Article