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Gamma Knife radiosurgery for the treatment of Nelson's syndrome: a multicenter, international study.

08:00 EDT 12th July 2019 | BioPortfolio

Summary of "Gamma Knife radiosurgery for the treatment of Nelson's syndrome: a multicenter, international study."

Nelson's syndrome is a rare and challenging neuroendocrine disorder, and it is associated with elevated adrenocorticotrophic hormone (ACTH) level, skin hyperpigmentation, and pituitary adenoma growth. Management options including resection and medical therapy are traditional approaches. Ionizing radiation in the form of Gamma Knife radiosurgery (GKRS) is also being utilized to treat Nelson's syndrome. In the current study the authors sought to better define the therapeutic role of stereotactic radiosurgery (SRS) in Nelson's syndrome.

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This article was published in the following journal.

Name: Journal of neurosurgery
ISSN: 1933-0693
Pages: 1-6

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A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.

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