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An in silico genome analysis of the probiotic Bacillus strain FTC01 was performed. The draft genome comprises 3.9 Mb, with a G + C content of 46.6% and a total of 3941 coding sequences. The species of strain FTC01 was defined as B. velezensis during GenBank genome annotation, following the current nomenclature. Eight gene clusters involved in the synthesis of non-ribosomal lipopeptides, polyketides and bacilysin were found, as well as part of the gene cluster involved in the synthesis of cyclic lipopeptide locillomycin. The production of lipopeptides surfactin and iturin by strain FTC01 was confirmed. In addition, a gene encoding a peptidylprolyl isomerase, involved in bacterial adhesion to the host tissue, beyond twelve genes responsible for acid tolerance and several hydrolase genes were found. These characteristics may help in host colonization and maintenance and may account for the probiotic properties observed for strain FTC01.
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An alkalophilic species of Bacillus that occurs in soil. It produces ANTI-BACTERIAL AGENTS and is used as a PROBIOTIC.
A microaerophilic, LACTIC ACID producing species of Bacillus that occurs in fermented foods. It also produces ANTI-INFECTIVE AGENTS and is used as a PROBIOTIC.
A non-pathogenic species of Bacillus that occurs in soil as well as some fermented vegetables and FERMENTED DAIRY PRODUCTS. It produces BACTERIOCINS and ANTIFUNGAL AGENTS and is used in FOOD PRESERVATION as well as a PROBIOTIC.
The parts of a GENOME sequence that are involved with the different functions or properties of genomes as a whole as opposed to those of individual GENES.
Viruses whose host is Bacillus. Frequently encountered Bacillus phages include bacteriophage phi 29 and bacteriophage phi 105.
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...