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Functional genome annotation depicts probiotic properties of Bacillus velezensis FTC01.

08:00 EDT 9th July 2019 | BioPortfolio

Summary of "Functional genome annotation depicts probiotic properties of Bacillus velezensis FTC01."

An in silico genome analysis of the probiotic Bacillus strain FTC01 was performed. The draft genome comprises 3.9 Mb, with a G + C content of 46.6% and a total of 3941 coding sequences. The species of strain FTC01 was defined as B. velezensis during GenBank genome annotation, following the current nomenclature. Eight gene clusters involved in the synthesis of non-ribosomal lipopeptides, polyketides and bacilysin were found, as well as part of the gene cluster involved in the synthesis of cyclic lipopeptide locillomycin. The production of lipopeptides surfactin and iturin by strain FTC01 was confirmed. In addition, a gene encoding a peptidylprolyl isomerase, involved in bacterial adhesion to the host tissue, beyond twelve genes responsible for acid tolerance and several hydrolase genes were found. These characteristics may help in host colonization and maintenance and may account for the probiotic properties observed for strain FTC01.

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This article was published in the following journal.

Name: Gene
ISSN: 1879-0038
Pages: 143971

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