Oleanane-type saponins from the roots of Parkia bicolor A. Chev.

08:00 EDT 9th July 2019 | BioPortfolio

Summary of "Oleanane-type saponins from the roots of Parkia bicolor A. Chev."

Five undescribed triterpene-type saponins, parkibicolorosides A-E, a cassane-type diterpene, and a known trimethoxy benzene glucoside were isolated from the roots of Parkia bicolor A. Chev. Their structures were elucidated by different spectroscopic methods including 1D- and 2D-NMR experiments as well as HR-ESI-MS analysis. Their cytotoxic activity against the chronic myeloid leukemia (K562) cell line was evaluated. The monosaccharides saponins exhibited a moderate antiproliferative activity with IC ranging from 48.49 ± 0.16 to 81.66 ± 0.17 μM.


Journal Details

This article was published in the following journal.

Name: Fitoterapia
ISSN: 1873-6971
Pages: 104264


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Medical and Biotech [MESH] Definitions

A plant genus of the family RANUNCULACEAE. Members contain cernuosides and other oleanane and hederagenin saponins.

A plant genus of the family MYRSINACEAE. Members contain ardisiacrispins (oleanane triterpenoid saponins), ardicrenin, and cyclamiretin.

A plant species of the genus PANAX. It contains damarane-type tetracyclic TRITERPENES. The common names of Sanchi or Tienchi are also used for Panax pseudoginseng which is distinguished in containing oleanane-type pentacyclic triterpenoids.

Root-like underground horizontal stem of plants that produces shoots above and roots below. Distinguished from true roots which don't have buds and nodes. Similar to true roots in being underground and thickened by storage deposits.

A type of neurofibroma manifesting as a diffuse overgrowth of subcutaneous tissue, usually involving the face, scalp, neck, and chest but occasionally occurring in the abdomen or pelvis. The tumors tend to progress, and may extend along nerve roots to eventually involve the spinal roots and spinal cord. This process is almost always a manifestation of NEUROFIBROMATOSIS 1. (From Adams et al., Principles of Neurology, 6th ed, p1016; J Pediatr 1997 Nov;131(5):678-82)

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