A randomized trial of nebulized lignocaine, lignocaine spray or their combination for topical anesthesia during diagnostic flexible bronchoscopy.

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Summary of "A randomized trial of nebulized lignocaine, lignocaine spray or their combination for topical anesthesia during diagnostic flexible bronchoscopy."

The optimal mode of delivering topical anesthesia during flexible bronchoscopy remains unknown. Herein, we compare the efficacy and safety of nebulized lignocaine, lignocaine oropharyngeal spray, or their combination.


Journal Details

This article was published in the following journal.

Name: Chest
ISSN: 1931-3543


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Medical and Biotech [MESH] Definitions

Work consisting of a clinical trial that involves at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.

Work consisting of a clinical trial involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicine, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trial is characterized as a RANDOMIZED CONTROLLED TRIAL.

Tests involving inhalation of allergens (nebulized or in dust form), nebulized pharmacologically active solutions (e.g., histamine, methacholine), or control solutions, followed by assessment of respiratory function. These tests are used in the diagnosis of asthma.

Works about randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and impacts.

Trial that aims to show a new treatment is no better and no worse than the standard treatment.

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