Quality Assurance of Dose Escalated Radiation Therapy in a Randomized Trial for Locally Advanced Oesophageal Cancer.

08:00 EDT 9th July 2019 | BioPortfolio

Summary of "Quality Assurance of Dose Escalated Radiation Therapy in a Randomized Trial for Locally Advanced Oesophageal Cancer."

The ongoing phase II/III XXX trial compares chemoradiotherapy with and without dose escalation in patients with locally advanced or unresectable oesophageal cancer. The results of a benchmark case procedure are reported here to evaluate the protocol compliance of participating centers as part of a quality assurance for radiation therapy (QART).


Journal Details

This article was published in the following journal.

Name: International journal of radiation oncology, biology, physics
ISSN: 1879-355X


DeepDyve research library

PubMed Articles [25104 Associated PubMed Articles listed on BioPortfolio]

Outcomes of a Dose-Escalated Stereotactic Body Radiation Phase I/II trial for Patients with Low and Intermediate-Risk Prostate Cancer.

This study presents a prospective phase I, IRB-approved dose-escalated stereotactic body radiotherapy (SBRT) trial for prostate cancer (CaP) to assess the impact of dose level on quality of life, toxi...

Spatial Dose Patterns Associated with Radiation Pneumonitis in a Randomized Trial Comparing Intensity-Modulated Radiation Therapy with Passive Scattering Proton Therapy for Locally Advanced Non-Small Cell Lung Cancer.

Radiation pneumonitis (RP) is commonly associated with thoracic radiation therapy (RT), and its incidence is related to dose and volume of the normal lung in the path of radiation. Our aim was to inve...

Radiation therapy dose de-escalation compared to standard dose radiation therapy in definitive treatment of HPV-positive oropharyngeal squamous cell carcinoma.

Despite existing evidence that human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) has a favorable prognosis compared to HPV-negative OPSCC, randomized studies have yet t...

Complementary relation between the improvement of dose delivery technique and PTV margin reduction in dose-escalated radiation therapy for prostate cancer.

The purpose of this work is to demonstrate quantitatively the complementary relation between the introduction of intensity-modulated radiation therapy (IMRT) and planning target volume (PTV) margin re...

Initial results of a randomized phase III trial of high dose image guided radiation with or without androgen deprivation therapy for intermediate-risk prostate cancer.

Prior randomized studies have shown a survival benefit using combined androgen deprivation therapy (ADT) and radiation therapy for intermediate-risk prostate cancer. However, these studies either used...

Clinical Trials [21018 Associated Clinical Trials listed on BioPortfolio]

Dose-Escalated Proton Radiation Therapy for High-Risk Prostate Cancer

The purpose of this research study is to determine if dose-escalated proton radiation therapy is a good way to treat high-risk prostate cancer. The study features hypofractionation and a s...

Dose Escalated Proton Beam Therapy or Photon Therapy for Esophageal Cancer

This study will evaluate if proton beam therapy as part of chemoradiation results in a decrease in diffusion lung capacity of carbon monoxide (DLCO) compared to photon radiation therapy fo...

Intensity Modulated Radiation Therapy (IMRT) Pelvic Nodes Prostate

The purpose of this study is to determine the feasibility and late toxicity of dose escalated radiation therapy to the pelvic lymph nodes and prostate and seminal vesicles in the treatment...

The Role of Tomotherapy in Hypofractionated/Dose Escalated Conformal Radiation Treatment for High Risk Prostate Cancer

Helical tomotherapy is being used to treat the prostate gland, local rates of spread and regional lymph nodes whilst sparing gross structures. The radiation to the gross disease in the pr...

Radiation With Chemotherapy and a Study Drug to the Para-Aortic Nodes in Cervical Cancer

Investigator has since decided not to pursue this protocol further. No patients were enrolled. This study is to determine the maximum tolerated dose of external beam radiation to the ...

Medical and Biotech [MESH] Definitions

The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).

Administration of the total dose of radiation (RADIATION DOSAGE) in parts, at timed intervals.

The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.

Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.

Quick Search

DeepDyve research library

Relevant Topics

  Bladder Cancer Brain Cancer Breast Cancer Cancer Cervical Cancer Colorectal Head & Neck Cancers Hodgkin Lymphoma Leukemia Lung Cancer Melanoma Myeloma Ovarian Cancer Pancreatic Cancer ...

Clincial Trials
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...

Cancer Disease
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer th...

Searches Linking to this Article