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A new study reports a synthetic bacterium that uses conjugation to transfer toxic genes that selectively kill pathogenic cells. The work represents a novel strategy for targeting pathogens, which could be the basis for a new generation of precision antimicrobials.
This article was published in the following journal.
Name: Molecular cell
Commensal microbes have mutualistic relationships with their host and mainly live in the host intestine. There are many studies on the relationships between commensal microbes and host physiology. How...
Koch's postulates and molecular Koch's postulates have made an indelible mark on how we study and classify microbes, particularly pathogens. However, rigid adherence to these historic postulates const...
The prevalence of celiac disease has increased in the last decades suggesting a role for environmental factors in addition to gluten. Several cohort studies have shown that different gastrointestinal ...
The proliferation of antibiotic resistance genes (ARGs) in drinking water and their potential horizontal transfer to pathogenic microbes may cause failure of antibiotics. However, antimicrobial resist...
Changes occurring in freshwater ecosystems seem to be fundamental in the development of all microorganisms, including those pathogenic to fish. This has been especially evident in recent years during ...
The main objective of this study is to characterize the evolution (over a period of 28 days) of superficial and deep bacterial skin flora in patients with stage 3 or 4 sacral pressure ulce...
While the maternal-newborn exchange of airway microbiota is well-documented, no studies have examined within-subject relationships among the mouth, sinuses, nasopharynx and lungs and the r...
Cirrhotic patients are predisposed to bacterial infection. A large proportion of which is spontaneous bacterial peritonitis(SBP), which are mainly caused by enteric bacteria.SBP in a cirr...
The goal of this study is characterize the changes in bacterial diversity of the upper respiratory tracts of infants with cystic fibrosis (CF). Another goal is to determine when CF patient...
The purpose of this study is to determine if the "Re-Engineered Discharge" will decrease rehospitalization rates and adverse events of patients leaving Boston Medical Center.
A non-pathogenic, obligate aerobic, Gram-negative species of Bdellovibrio that occurs in water and soil, as well as the intestines of birds and mammals. It can infect and lyse pathogenic GRAM-NEGATIVE BACTERIA and can function as a PROBIOTIC and ANTI-BACTERIAL AGENT.
An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of pathogenic bacteria. Some capsules have a well-defined border, whereas others form a slime layer that trails off into the medium. Most capsules consist of relatively simple polysaccharides but there are some bacteria whose capsules are made of polypeptides.
A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.
Bacterial vaccines prepared from non-pathogenic, autologous bacteria of human origin. In Eastern Europe they are used in humans to treat chronic inflammatory disorders that are resistant to standard treatments. Worldwide they have veterinary use in all types of infectious disease.
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.