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Whole-Cell Models and Simulations in Molecular Detail.

08:00 EDT 12th July 2019 | BioPortfolio

Summary of "Whole-Cell Models and Simulations in Molecular Detail."

Comprehensive data about the composition and structure of cellular components have enabled the construction of quantitative whole-cell models. While kinetic network-type models have been established, it is also becoming possible to build physical, molecular-level models of cellular environments. This review outlines challenges in constructing and simulating such models and discusses near- and long-term opportunities for developing physical whole-cell models that can connect molecular structure with biological function. Expected final online publication date for the Volume 35 is October 7, 2019. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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Name: Annual review of cell and developmental biology
ISSN: 1530-8995
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