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Human myometrial artery function and endothelial cell calcium signalling are reduced by obesity: can this contribute to poor labour outcomes?

08:00 EDT 12th July 2019 | BioPortfolio

Summary of "Human myometrial artery function and endothelial cell calcium signalling are reduced by obesity: can this contribute to poor labour outcomes?"

Determining how obesity affects function in human myometrial arteries, to help understand why childbirth has poor outcomes in obese women.

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This article was published in the following journal.

Name: Acta physiologica (Oxford, England)
ISSN: 1748-1716
Pages: e13341

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Medical and Biotech [MESH] Definitions

A fluorescent calcium chelating agent which is used to study intracellular calcium in many tissues. The fluorescent and chelating properties of Fura-2 aid in the quantitation of endothelial cell injury, in monitoring ATP-dependent calcium uptake by membrane vesicles, and in the determination of the relationship between cytoplasmic free calcium and oxidase activation in rat neutrophils.

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Endovascular reconstruction of an artery, which may include the removal of atheromatous plaque and/or the endothelial lining as well as simple dilatation. These are procedures performed by catheterization. When reconstruction of an artery is performed surgically, it is called ENDARTERECTOMY.

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A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their precursors. VEGFR-2 is important for vascular and hematopoietic development, and mediates almost all endothelial cell responses to VEGF.

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