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An apparent paradox: resistance mutations in HIV-1 DNA predict improved virological responses to antiretroviral therapy.

08:00 EDT 12th July 2019 | BioPortfolio

Summary of "An apparent paradox: resistance mutations in HIV-1 DNA predict improved virological responses to antiretroviral therapy."

In sub-Saharan Africa, detecting resistance-associated mutations (RAMs) at failure of first-line ART with two NRTIs plus an NNRTI predicts improved virological responses to second-line therapy with two NRTIs plus a ritonavir-boosted PI (PI/r). This indicates residual NRTI activity in the presence of RAMs, although additional factors may contribute to the effect.

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Name: The Journal of antimicrobial chemotherapy
ISSN: 1460-2091
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Bioinformatics
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...

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