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Gold(I)-Catalyzed Synthesis of Furopyrans: Insight into Hetero-Diels-Alder Reactions.

08:00 EDT 12th July 2019 | BioPortfolio

Summary of "Gold(I)-Catalyzed Synthesis of Furopyrans: Insight into Hetero-Diels-Alder Reactions."

We report herein the synthesis of complex molecules containing furopyran cores through a gold(I)-catalyzed hetero-Diels-Alder cascade reaction. During this process, the diene and the dienophile are produced concomitantly by the action of a single catalyst from a single starting material. Moreover, six bonds, four heterocycles, and four controlled stereogenic centers are formed in a one-step operation. DFT calculations provide the mechanistic basis of this unprecedented reaction.

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Name: Organic letters
ISSN: 1523-7052
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Medical and Biotech [MESH] Definitions

Used in copolymerization reactions, in the Diels-Alder(diene)synthesis, in the preparation of resins, pharmaceuticals and agricultural chemicals. It is a powerful irritant and causes burns.

Unstable isotopes of gold that decay or disintegrate emitting radiation. Au 185-196, 198-201, and 203 are radioactive gold isotopes.

Stable gold atoms that have the same atomic number as the element gold, but differ in atomic weight. Au-197 is a stable isotope.

A suspension of metallic gold particles.

Inorganic compounds that contain gold as an integral part of the molecule.

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