SERPINA1 gene polymorphisms in a population-based ALSPAC cohort.

08:00 EDT 12th July 2019 | BioPortfolio

Summary of "SERPINA1 gene polymorphisms in a population-based ALSPAC cohort."

There is an association between persistent preschool wheezing phenotypes and school-age asthma. These wheezing/asthma phenotypes likely represent clinical entities having specific genetic risk factors. The SERPINA1 gene encodes α -antitrypsin (AAT), and mutations in the gene are important in the pathophysiology of pulmonary diseases. We hypothesized that there might be an association between SERPINA1 gene polymorphisms and the risk of developing wheezing/school age asthma.


Journal Details

This article was published in the following journal.

Name: Pediatric pulmonology
ISSN: 1099-0496


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