Reflectance confocal microscopy may enhance the accuracy of histopathologic diagnosis: a case series.

08:00 EDT 12th July 2019 | BioPortfolio

Summary of "Reflectance confocal microscopy may enhance the accuracy of histopathologic diagnosis: a case series."

Although histopathology is the time-honored gold standard diagnostic measure in dermatology, several factors may detract from an accurate microscopic diagnosis. Limiting factors include: human error, suboptimal biopsy-site selection or biopsy technique, and inherent restrictions of vertical tissue sectioning that lead to incomplete microscopic evaluation of the lesion. Reflectance confocal microscopy (RCM) is a non-invasive imaging tool that allows for the cellular-level examination of the lesion, at a horizontal plane, which may complement the subsequent vertical histopathological tissue examination. Herein, we report a case series whereby pre-biopsy RCM examination enhanced the accuracy of histopathological diagnosis or allowed for a critical appraisal of initial histopathological misdiagnosis. This article is protected by copyright. All rights reserved.


Journal Details

This article was published in the following journal.

Name: Journal of cutaneous pathology
ISSN: 1600-0560


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