Propofol Sedation Alters Perceptual and Cognitive Functions in Healthy Volunteers as Revealed by Functional Magnetic Resonance Imaging.

08:00 EDT 1st August 2019 | BioPortfolio

Summary of "Propofol Sedation Alters Perceptual and Cognitive Functions in Healthy Volunteers as Revealed by Functional Magnetic Resonance Imaging."

Loss of consciousness during anesthesia is associated with a loss of anterior-posterior connectivityHowever, during anesthesia local sensory cortex function may be preserved WHAT THIS ARTICLE TELLS US THAT IS
During propofol sedation, activation on functional magnetic resonance imaging in higher cognitive areas, such as semantic and phonologic processing, is abolished with deep sedation and only partially suppressed with light sedationActivation related to lower sensory processing continues with deep and light sedation
: Elucidating networks underlying conscious perception is important to understanding the mechanisms of anesthesia and consciousness. Previous studies have observed changes associated with loss of consciousness primarily using resting paradigms. The authors focused on the effects of sedation on specific cognitive systems using task-based functional magnetic resonance imaging. The authors hypothesized deepening sedation would degrade semantic more than perceptual discrimination.


Journal Details

This article was published in the following journal.

Name: Anesthesiology
ISSN: 1528-1175
Pages: 254-265


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