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Since 2011, 2% chlorhexidine in 70% isopropyl alcohol (2% chlorhexidine tincture) has been widely used in Korea. To investigate changes in chlorhexidine sensitivity of staphylococci causing central line-associated bloodstream infections, 264 blood culture isolates from adult patients treated in intensive care units of five university hospitals between 2008 and 2016 were analyzed. We observed no significant changes in chlorhexidine minimum inhibitory and bactericidal concentrations, or in the prevalence of resistance-associated genes before and after introduction of 2% chlorhexidine tincture. Thus, there was no evidence of increased resistance to chlorhexidine in staphylococci causing central line-associated bloodstream infections.
This article was published in the following journal.
Name: The Journal of hospital infection
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A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
A term used in Eastern European research literature for the functional neural unit that provides the basis for differential sensitivity; the analyzer consists of receptor, afferent nerves, and their central connections. (From Campbell's Psychiatric Dictionary, 8th ed.)
Inflammation of ARTERIES in the CENTRAL NERVOUS SYSTEM that occurs in patients with ACQUIRED IMMUNODEFICIENCY SYNDROME or AIDS-RELATED OPPORTUNISTIC INFECTIONS.
An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.
A species of ALPHAVIRUS isolated in central, eastern, and southern Africa.
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