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Perianal sepsis is one of the most challenging diseases for the colorectal surgeon. The management of this pathology can be associated with high morbidity. Incorrect diagnosis is quite common with consequent improper drainage. This leads to a high number of recurrences, and the need for re-operation has been described in up to 50% of cases (1). When perianal sepsis is of cryptoglandular origin, it begins at the level of the dentate line, from where it could spread to the different perianal spaces and develop the submucous, intersphincteric or transsphicteric abscess. This article is protected by copyright. All rights reserved.
This article was published in the following journal.
Name: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Complex perianal fistulas represent one of the most challenging manifestations of Crohn's disease. Combined surgical and medical therapy with biologic drugs today represent the first-line treatment op...
In this study, we aimed to evaluate outcomes of % 20 silver nitrate (SNS) application in perianal fistula patients.
Contrary to historical teaching about addressing very distal retrorectal (presacral) cysts via perianal incision, our preferred, current method for treating most of these lesions involves a robotic ab...
Few data are published on perianal tuberculosis.
Perianal abscess is a common surgical condition in the daily pediatric practice. Management is a subject of controversy and variety of approaches are practiced. While the most frequent approach is dra...
Phase of Investigation: First-in-human feasibility study Objectives: Primary objective: Demonstration that TIPS microspheres do not compromise the clinical condition or safety of the pati...
This study is an extension to re-treat partial and non-responders from the previously approved Phase 1 MCS-AFP protocols IRB #12-009716 (Crohn's Disease perianal fistulas) and 15-003200 (c...
The aim of this trial is to compare internal wound packing to no packing in postoperative management following incision and drainage of perianal abscess. Participants will be randomised 1:...
The aim of this study is to evaluate whether a local perianal block performed during a proctological intervention can reduce the postoperative pain.
The primary objectives of this trial are: - To explore the pathomechanisms involved in the generation and healing of Crohn's Disease (CD) associated perianal fistulas - ...
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Acute neurological dysfunction during severe SEPSIS in the absence of direct brain infection characterized by systemic inflammation and BLOOD BRAIN BARRIER perturbation.
Blood infection that occurs in an infant younger than 90 days old. Early-onset sepsis is seen in the first week of life and most often appears within 24 hours of birth. Late-onset occurs after 1 week and before 3 months of age.
A type of SEBACEOUS GLAND located in the area surrounding the ANUS of some mammals such as dogs, cats, opossums, and guinea pigs.
A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.
Antiretroviral Therapy Clostridium Difficile Ebola HIV & AIDS Infectious Diseases Influenza Malaria Measles Sepsis Swine Flu Tropical Medicine Tuberculosis Infectious diseases are caused by pathogenic...
Sepsis, septicaemia and blood poisoning
Septicaemia (another name for blood poisoning) refers to a bacterial infection of the blood, whereas sepsis can also be caused by viral or fungal infections. Sepsis is not just limited to the blood and can affect the whole body, including the organ...