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Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.

08:00 EDT 17th July 2019 | BioPortfolio

Summary of "Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations."

Genetic variation has an important role in the development of non-small-cell lung cancer (NSCLC). However, genetic factors for lung cancer have not been fully identified, especially in Chinese populations, which limits the use of existing polygenic risk scores (PRS) to identify subpopulations at high risk of lung cancer for prevention. We therefore aimed to identify novel loci associated with NSCLC risk, and generate a PRS and evaluate its utility and effectiveness in the prediction of lung cancer risk in Chinese populations.

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This article was published in the following journal.

Name: The Lancet. Respiratory medicine
ISSN: 2213-2619
Pages:

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