A three-sample test for introgression.

08:00 EDT 2nd August 2019 | BioPortfolio

Summary of "A three-sample test for introgression."

Many methods exist for detecting introgression between non-sister species, but the most commonly used require either a single sequence from four or more taxa or multiple sequences from each of three taxa. Here we present a test for introgression that uses only a single sequence from three taxa. This test, denoted D3, uses similar logic as the standard D-test for introgression, but by using pairwise distances instead of site patterns it is able to detect the same signal of introgression with fewer species. We use simulations to show that D3 has statistical power almost equal to D, demonstrating its use on a dataset of wild bananas (Musa). The new test is easy to apply and easy to interpret, and should find wide use among currently available datasets.


Journal Details

This article was published in the following journal.

Name: Molecular biology and evolution
ISSN: 1537-1719


DeepDyve research library

PubMed Articles [9053 Associated PubMed Articles listed on BioPortfolio]

Polygenic patterns of adaptive introgression in modern humans are mainly shaped by response to pathogens.

Anatomically modern humans carry many introgressed variants from other hominins in their genomes. Some of them affect their phenotype and can thus be negatively or positively selected. Several individ...

A Bayesian implementation of the multispecies coalescent model with introgression for phylogenomic analysis.

Recent analyses suggest that cross-species gene flow or introgression is common in nature, especially during species divergences. Genomic sequence data can be used to infer introgression events and to...

Hybridization between two parapatric ranid frog species in the northern Sierra Nevada, California, USA.

Contact zones between species provide a unique opportunity to test whether taxa can hybridize or not. Cross-breeding or hybridization between closely related taxa can promote gene flow (introgression)...

Massive introgression of MHC genes in newt hybrid zones.

Variation in the vertebrate major histocompatibility complex (MHC) genes is crucial for fighting pathogen assault. Because new alleles confer a selective advantage, MHC should readily introgress betwe...

Determinants of non-participation in colon examination following positive stool sample in colorectal cancer screening.

Social inequalities has been shown for participation in colorectal cancer screening and recently in the initial stool sample blood test. If these differences persist at follow-up colon examination aft...

Clinical Trials [4974 Associated Clinical Trials listed on BioPortfolio]

Clinical Evaluation of the IONA Test for Non-invasive Pre Natal Screening in Twin Pregnancies

The purpose of this study is to evaluate the performance of the IONA® test which is a non-invasive prenatal test (NIPT) for Down's syndrome and other chromosomal abnormalities in twin pre...

Screening for Prediabetes

People who might have prediabetes or unrecognized diabetes will be screened for these problems at an outpatient visit. For screening, they will take a sugary drink containing 50 grams of ...

Project-0027. Lay User Usage Study

Study volunteers will be required to conduct a home pregnancy test (HPT) at the trial centre and provide a sample of urine from the same void for further testing. Volunteers will then com...

Screening Protocol for Tumor Antigen Expression and HLA Sub-Type in NSCLC

This screening study is intended for men and women at least 18 years of age who have advanced or metastatic lung cancer. The study will assess a subject's tumor antigen expression profile ...

Study With Candida Antigen for Treatment of Warts

The purpose of this study is to look at how people respond to the treatment of warts through use of the Candida Antigen to get an immune response to rid the body of human papillomavirus (H...

Medical and Biotech [MESH] Definitions

An immunoenzyme test for the presence of drugs and other substances in urine and blood. The test uses enzyme linked antibodies that react only with the particular drug for which the sample is being tested.

Tests designed to assess language behavior and abilities. They include tests of vocabulary, comprehension, grammar and functional use of language, e.g., Development Sentence Scoring, Receptive-Expressive Emergent Language Scale, Parsons Language Sample, Utah Test of Language Development, Michigan Language Inventory and Verbal Language Development Scale, Illinois Test of Psycholinguistic Abilities, Northwestern Syntax Screening Test, Peabody Picture Vocabulary Test, Ammons Full-Range Picture Vocabulary Test, and Assessment of Children's Language Comprehension.

The analysis of a chemical substance by inserting a sample into a carrier stream of reagent using a sample injection valve that propels the sample downstream where mixing occurs in a coiled tube, then passes into a flow-through detector and a recorder or other data handling device.

A type of scanning probe microscopy in which a very sharp conducting needle is swept just a few angstroms above the surface of a sample. The tiny tunneling current that flows between the sample and the needle tip is measured, and from this are produced three-dimensional topographs. Due to the poor electron conductivity of most biological samples, thin metal coatings are deposited on the sample.

A projective test used to evaluate a broad range of personality variables including pathology of thought and perception. The subject's responses to inkblot prints are scored along with subjective interpretation by the test administrator.

Quick Search

DeepDyve research library

Searches Linking to this Article