Improving Volume Overload on Home Blood Pressure Variability in Hemodialysis Patients.

08:00 EDT 5th August 2019 | BioPortfolio

Summary of "Improving Volume Overload on Home Blood Pressure Variability in Hemodialysis Patients."

Blood pressure variability is an independent predictor of adverse clinical events in hemodialysis patients. Volume overload is one of the most important factors affecting blood pressure homeostasis. In the present study, we explored the effects of dry weight reduction on home blood pressure variability in volume overload hemodialysis patients. Hemodialysis patients with volume overload had their dry weight gradually decreased under the guidance of bioimpedance methods, which was represented by calf bioimpedance ratio (Calf-BR). Home blood pressure was measured on waking up and at bedtime for one week at baseline and at the end of the two-month study. Coefficient of variation was used to define home blood pressure variability. Thirty-eight hemodialysis patients had their dry weight significantly decreased from 60.7 ± 11.3 to 59.6 ± 10.7 (p = 0.003) accompanied with a significant reduction in calf-BR (0.828 ± 0.023 versus 0.786 ± 0.020, p<0.001). The systolic and diastolic blood pressure decreased significantly. Moreover, the whole-day, morning and evening systolic blood pressure variability gradually and significantly decreased by the end of the study (5.6 ± 2.1 versus 4.0 ± 1.7, p<0.001; 7.7 ± 3.5% versus 6.3 ± 2.7%, p = 0.005; 7.5 ± 2.8% versus 5.9 ± 2.3%, p = 0.002, respectively). Diastolic blood pressure variability parameters were unchanged. The interdialytic weight gain and the incidence of adverse events were similar throughout the study period. Gradually dry weight reduction by bioimpedance methods improved home blood pressure variability in hemodialysis patients with chronic fluid overload. This article is protected by copyright. All rights reserved.


Journal Details

This article was published in the following journal.

Name: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
ISSN: 1744-9987


DeepDyve research library

PubMed Articles [18070 Associated PubMed Articles listed on BioPortfolio]

The relationship of volume overload and its control to hypertension in hemodialysis patients.

Hypertension is highly prevalent and associated with poor clinical outcomes among individuals receiving maintenance hemodialysis (HD). Volume overload is a key modifiable contributor to hypertension a...

Comparison between clinical judgment and integrated lung and inferior vena cava ultrasonography for dry weight estimation in hemodialysis patients.

Correct dry weight estimation is very crucial for hemodialysis (HD) patients to maintain euvolemia. Most dialysis centers practice clinical judgment for dry weight estimation, which is subjective and ...

The effects of preoperative blood pressure on early failure rate of distal arteriovenous fistulas for hemodialysis access.

The first choice of vascular access for hemodialysis in patients with end-stage renal disease is a distal radiocephalic arteriovenous fistula (AVF). Early failure rates for these AVFs vary from 10% to...

Relation of short-term blood pressure variability to early renal effects in hypertensive patients with controlled blood pressure.

Microalbuminuria is a common early hypertension-mediated organ damage, which correlates with the overall cardiovascular risk and development of end-stage renal damage. Lately, blood pressure variabili...

Assessing the role of extracellular signal-regulated kinases 1 and 2 in volume overload-induced cardiac remodelling.

Volume overload (VO) and pressure overload (PO) induce differential cardiac remodelling responses including distinct signalling pathways. Extracellular signal-regulated kinases 1 and 2 (ERK1/2), key s...

Clinical Trials [17213 Associated Clinical Trials listed on BioPortfolio]

Effects Of Volume Control Guided by Body Composition Monitor (BCM) on Blood Pressure and Cardiac Condition in Hemodialysis Patients

This prospective, randomized, controlled study aims to evaluate the usefulness of the new body composition monitor (BCM) device as a method to improve volume control in hemodialysis (HD) p...

Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis

Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiogr...

Timing of Antihypertensive Medications on Key Outcomes in Hemodialysis

For patients with kidney failure requiring hemodialysis treatment, sometimes the blood pressure will drop too low during dialysis. In an effort to prevent that from occurring, patients are...

A Study in the Use of Home Blood Pressure Monitoring and Telephone Follow-up to Control Blood Pressure

The purpose of this study is to determine if the use of home blood pressure monitors plus nurse telephone monitoring is more effective than the use of blood pressure monitors alone in impr...

A Study to Define the Distribution of Type of Hypertension in Asia by Blood Pressure Monitoring at Home (Asia BP@Home)

Blood pressure variability (BPV) is being increasingly recognized as an important influence on hypertension outcomes as well as a risk factor for other cardiovascular (CV) events. However,...

Medical and Biotech [MESH] Definitions

Long-term maintenance hemodialysis in the home.

A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.

The measure of a BLOOD VESSEL's ability to increase the volume of BLOOD it holds without a large increase in BLOOD PRESSURE. The vascular capacitance is equal to the change in volume divided by the change in pressure.

Phenomenon where increased BLOOD PRESSURE readings taken in non-clinical settings (e.g., HOME BLOOD PRESSURE MONITORING) do not replicate in clinical settings.

Extracorporeal ultrafiltration technique without hemodialysis for treatment of fluid overload and electrolyte disturbances affecting renal, cardiac, or pulmonary function.

Quick Search

DeepDyve research library

Searches Linking to this Article