Medicinal Complex Therapy - Drug Interaction of Valproate and Dipyrone.

08:00 EDT 14th August 2019 | BioPortfolio

Summary of "Medicinal Complex Therapy - Drug Interaction of Valproate and Dipyrone."

The clinical relevance of the drug interaction between valproic acid and dipyrone is presented in the context of a gerontopsychiatric case. It is assumed that dipyrone at a dose of 4 g/d has a relevant influence on the valproate level and the associated clinical outcome. This may be due to a possible induction of CYP2B6 and increased valproate metabolism. In the case of a treatment of valproate combined with dipyrone, a close monitoring of the valproate level is recommended.


Journal Details

This article was published in the following journal.

Name: Psychiatrische Praxis
ISSN: 1439-0876


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