An orally administered magnoloside A ameliorates functional dyspepsia by modulating brain-gut peptides and gut microbiota.

08:00 EDT 11th August 2019 | BioPortfolio

Summary of "An orally administered magnoloside A ameliorates functional dyspepsia by modulating brain-gut peptides and gut microbiota."

Functional dyspepsia (FD) is very common worldwide with a high prevalence of 10%-30%, and it becomes a heavy burden to patients because of its hard to be cured. In our previous study, phenylethanoid glycosides were found to exist in Houpo, a traditional Chinese medicine commonly used for the treatment of abdominal distention, pain and dyspepsia. In the present study, the effect of magnoloside A (MA), a main phenylethanoid glycoside in Houpo, on FD was firstly evaluated and its potential mechanism was concluded.


Journal Details

This article was published in the following journal.

Name: Life sciences
ISSN: 1879-0631
Pages: 116749


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Medical and Biotech [MESH] Definitions

A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)

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Fixed drug combinations administered orally for contraceptive purposes.

A benzeneacetamide with anti-inflammatory, analgesic, and antipyretic action. It is administered topically, orally, or rectally.

A powder that dissolves in water, which is administered orally, and is used as a diuretic, expectorant, systemic alkalizer, and electrolyte replenisher.

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