Topics

The "All of Us" Research Program.

08:00 EDT 15th August 2019 | BioPortfolio

Summary of "The "All of Us" Research Program."

Knowledge gained from observational cohort studies has dramatically advanced the prevention and treatment of diseases. Many of these cohorts, however, are small, lack diversity, or do not provide comprehensive phenotype data. The All of Us Research Program plans to enroll a diverse group of at least 1 million persons in the United States in order to accelerate biomedical research and improve health. The program aims to make the research results accessible to participants, and it is developing new approaches to generate, access, and make data broadly available to approved researchers. All of Us opened for enrollment in May 2018 and currently enrolls participants 18 years of age or older from a network of more than 340 recruitment sites. Elements of the program protocol include health questionnaires, electronic health records (EHRs), physical measurements, the use of digital health technology, and the collection and analysis of biospecimens. As of July 2019, more than 175,000 participants had contributed biospecimens. More than 80% of these participants are from groups that have been historically underrepresented in biomedical research. EHR data on more than 112,000 participants from 34 sites have been collected. The All of Us data repository should permit researchers to take into account individual differences in lifestyle, socioeconomic factors, environment, and biologic characteristics in order to advance precision diagnosis, prevention, and treatment.

Affiliation

Journal Details

This article was published in the following journal.

Name: The New England journal of medicine
ISSN: 1533-4406
Pages: 668-676

Links

DeepDyve research library

PubMed Articles [12322 Associated PubMed Articles listed on BioPortfolio]

Training program for Research Educators of sequential course-based undergraduate research experiences.

Science education studies have shown that a sequence of course-based research experiences (CURE) has many positive effects for undergraduates. To maximize those benefits, we created a training program...

Design and Implementation of an Infrastructure Program to Support Clinical Research in Surgery.

Barriers to active participation in clinical research among academic surgeons include insufficient research training and mentorship, increased clinical demands, lack of protected research time, limite...

Three Lidcombe program clinic visit options: a phase II trial.

Weekly clinic visits are recommended in the Lidcombe Program Treatment Guide (Packman et al., 2015). That specification is based on traditional speech-language pathology practices rather than empirica...

Network analysis to evaluate the impact of research funding on research community consolidation.

In 2004, the Alfred P. Sloan Foundation launched a new program focused on incubating a new field, "Microbiology of the Built Environment" (MoBE). By the end of 2017, the program had supported the publ...

Practice-Based Nursing Research: Evaluation of clinical and professional impacts from a research training program.

To determine the clinical and professional impacts of nurses' and other clinicians' involvement in a research training program.

Clinical Trials [6033 Associated Clinical Trials listed on BioPortfolio]

Sustainability of a Research Program in Risk Management (PeRENNITe)

Sustainability can be defined by several dimensions: the pursuit of program elements, the maintenance of its effectiveness, its integration into work processes, the adaptation of the progr...

Effect of a Prevention Program on Program Facilitators

The study will examine, through quantitative and qualitative research, how the delivery of the program "In Favor of Myself" to school children influences the program facilitators themselve...

Development of Eating Disorders Symptoms Among Children

Randomized Clinical Trial, the research will be composed of two parts in order to examine the research question: a combination of controlled randomized retrospective research and prospecti...

In-School Evaluation of Bystander: A Game-Based Intervention for Sexual Violence Prevention

The investigators have developed a game-based sexual violence prevention program that uses a bystander intervention approach. This program is called Bystander and was designed for use with...

Evaluation of a Living With Hope Program

The Living with Hope program was developed by the research team, a panel of experts and palliative patients and their families. The program was evaluated with 60 advanced cancer patients 6...

Medical and Biotech [MESH] Definitions

The process of formulating, improving, and expanding educational, managerial, or service-oriented work plans (excluding computer program development).

Evaluation of the degree of acceptance for the immediate variables associated with a procedure or program designed to change behavior. This includes the social significance of the goals of treatment, the social appropriateness of the treatment procedures, and the social importance of the effects of treatments.

A center in the PUBLIC HEALTH SERVICE which coordinates and administers a program of research, demonstrations, and evaluations of medical technologies and assessments of health care technology.

A two-year program in nursing education in a community or junior college leading to an A.D. (Associate Degree). Graduates of this program are eligible for state examination for licensure as RN (Registered Nurse).

Component of the NATIONAL INSTITUTES OF HEALTH. It seeks to improve oral, dental and craniofacial health through research, research training, and the dissemination of health information by conducting and supporting basic and clinical research. It was established in 1948 as the National Institute of Dental Research and re-named in 1998 as the National Institute of Dental and Craniofacial Research.

Quick Search


DeepDyve research library

Searches Linking to this Article